Overview of keratopathy:
The intact corneal epithelium (surface layer of the eye) serves as a barrier against ocular infection, and contributes to the maintenance of corneal transparency and rigidity. Injury to this surface layer of the eye requires prompt resurfacing in order to re-establish visual function. Unlike patients without diabetes who have corneal surface defects that rapidly heal, individuals with diabetes present with corneal surface defects that may persist and be unresponsive to conventional treatment regimens. This complication is known as diabetes-related keratopathy.