Insulin is the mainstay therapy for T1D. New types of insulin, modern glucose monitoring, and insulin administration techniques have made it easier for insulin levels in patients with type 1 diabetes to more closely mimic those in healthy individuals. Insulin treatment can be rapid acting, short acting, intermediate acting and long acting, these may be administered via daily injections and/or insulin pumps which reduce the frequency of injections.
The use of non-insulin add-on treatment is a new trend. It has been successfully used in laboratories as well as clinical trials. Metformin is the most widely used drug, together with sodium-glucose co-transporters 2 (SGLT2) inhibitors, amylin analogues, glucagon-like peptide 1 (GLP-1) receptor agonists, and dipeptidyl peptidase-4 (DPP-4) inhibitors. The results of administration of these medications give good outcomes in patients with T1D.